From I-64: West on Highway 94 to Highway 47. Go north 2.5 miles to Marthasville. Turn right about a quarter mile, cross the Katy Trail. The first street after the trail is Depot Street. Follow it west for 4 blocks. Visit The Little House Soon! We are located in Marthasville, Missouri, about 60 miles west of St. Louis. Directions to The Little House From I-70: Take the Warrenton exit (193). Turn south on Highway 47 for 16 miles to Marthasville. Turn left onto Highway D and follow it approximately 2 blocks. The Little House is on your left. From I-44: Take the Washington exit (251). Go west on Highway 100 for 10 miles to Washington. Turn north on Highway 47 for 7 miles to Marthasville. Turn right about a quarter mile, cross the Katy Trail. The first street after the trail is Depot Street. Follow it west (left) for 4 blocks.